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human neuroblastoma cell line imr5  (Inserm Transfert)

 
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    Inserm Transfert human neuroblastoma cell line imr5
    Human Neuroblastoma Cell Line Imr5, supplied by Inserm Transfert, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+neuroblastoma+cell+line+imr5/neuroblastoma+cell+lines/pm34023958-51-1-13
    Average 90 stars, based on 1 article reviews
    human neuroblastoma cell line imr5 - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Cell Culture:

    Article Title: SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells
    Article Snippet: Isotretinoin (13- cis -retinoic acid) was purchased from Sigma Aldrich (Saint Louis, MO, USA). .. Cell culture The human neuroblastoma cell line IMR5 was generously provided by Dr. Santos Susin (Inserm U.872, Paris, France) and the human neuroblastoma cell line LAN1 was obtained from the Children’s Oncology Group Cell Culture and Xenograft Repository (Philadelphia, PA, USA). ..

    Article Title: SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells.
    Article Snippet: Immunotherapy with anti-GD2 monoclonal antibodies (mAbs) provides some benefits for patients with neuroblastoma (NB).. However, the therapeutic efficacy remains limited, and treatment is associated with significant neuropathic pain.. Targeting O-acetylated GD2 (OAcGD2) by 8B6 mAb has been proposed to avoid pain by more selective tumor cell targeting.



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    human neuroblastoma cell line imr5  (Inserm Transfert)
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    Inserm Transfert human neuroblastoma cell line imr5
    Human Neuroblastoma Cell Line Imr5, supplied by Inserm Transfert, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ( A ) Representative flow cytometry images of IMR5, SK-N-AS and <t>SY5Y</t> cells treated with fosaprepitant or control for 72 h and stained for Annexin V and DAPI. Gates show viable cells (DAPI negative, Annexin V negative), early apoptotic cells (DAPI negative, Annexin V positive) and late apoptotic cells (DAPI positive, Annexin V positive) after treatment with fosaprepitant or control. ( B ) Proliferation of cells monitored in real time using the Xcilligance system after fosaprepitant treatment compared with cells treated with Meglumine control ( n = 3, line represents mean value). ( C ) Fraction of cells in each point of the cell cycle measured after 48 h of treatment with fosaprepitant or meglumine (control). ( D ) Bar graph showing cell viability in MTT assays of IMR5 cells treated with 5 μM fosaprepitant or control for 72 h as well as combined fosaprepitant and substance P treatment for 72 h (+ = 100 nM Substance P, ++ = 500 nM Substance P, n = 3, error bars represent the standard deviation)(100nM vs. no substance P, p = 0.0013; 500 nM vs. no substance P, p = 0.0006).
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    human neuroblastoma imr5 cell line  (Inserm Transfert)
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    ( A ) Representative flow cytometry images of IMR5, SK-N-AS and <t>SY5Y</t> cells treated with fosaprepitant or control for 72 h and stained for Annexin V and DAPI. Gates show viable cells (DAPI negative, Annexin V negative), early apoptotic cells (DAPI negative, Annexin V positive) and late apoptotic cells (DAPI positive, Annexin V positive) after treatment with fosaprepitant or control. ( B ) Proliferation of cells monitored in real time using the Xcilligance system after fosaprepitant treatment compared with cells treated with Meglumine control ( n = 3, line represents mean value). ( C ) Fraction of cells in each point of the cell cycle measured after 48 h of treatment with fosaprepitant or meglumine (control). ( D ) Bar graph showing cell viability in MTT assays of IMR5 cells treated with 5 μM fosaprepitant or control for 72 h as well as combined fosaprepitant and substance P treatment for 72 h (+ = 100 nM Substance P, ++ = 500 nM Substance P, n = 3, error bars represent the standard deviation)(100nM vs. no substance P, p = 0.0013; 500 nM vs. no substance P, p = 0.0006).
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    human neuroblastoma cell line imr5  (Marburg GmbH)
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    ( A ) Representative flow cytometry images of IMR5, SK-N-AS and <t>SY5Y</t> cells treated with fosaprepitant or control for 72 h and stained for Annexin V and DAPI. Gates show viable cells (DAPI negative, Annexin V negative), early apoptotic cells (DAPI negative, Annexin V positive) and late apoptotic cells (DAPI positive, Annexin V positive) after treatment with fosaprepitant or control. ( B ) Proliferation of cells monitored in real time using the Xcilligance system after fosaprepitant treatment compared with cells treated with Meglumine control ( n = 3, line represents mean value). ( C ) Fraction of cells in each point of the cell cycle measured after 48 h of treatment with fosaprepitant or meglumine (control). ( D ) Bar graph showing cell viability in MTT assays of IMR5 cells treated with 5 μM fosaprepitant or control for 72 h as well as combined fosaprepitant and substance P treatment for 72 h (+ = 100 nM Substance P, ++ = 500 nM Substance P, n = 3, error bars represent the standard deviation)(100nM vs. no substance P, p = 0.0013; 500 nM vs. no substance P, p = 0.0006).
    Human Neuroblastoma Cell Line Imr5, supplied by Marburg GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ( A ) Representative flow cytometry images of IMR5, SK-N-AS and SY5Y cells treated with fosaprepitant or control for 72 h and stained for Annexin V and DAPI. Gates show viable cells (DAPI negative, Annexin V negative), early apoptotic cells (DAPI negative, Annexin V positive) and late apoptotic cells (DAPI positive, Annexin V positive) after treatment with fosaprepitant or control. ( B ) Proliferation of cells monitored in real time using the Xcilligance system after fosaprepitant treatment compared with cells treated with Meglumine control ( n = 3, line represents mean value). ( C ) Fraction of cells in each point of the cell cycle measured after 48 h of treatment with fosaprepitant or meglumine (control). ( D ) Bar graph showing cell viability in MTT assays of IMR5 cells treated with 5 μM fosaprepitant or control for 72 h as well as combined fosaprepitant and substance P treatment for 72 h (+ = 100 nM Substance P, ++ = 500 nM Substance P, n = 3, error bars represent the standard deviation)(100nM vs. no substance P, p = 0.0013; 500 nM vs. no substance P, p = 0.0006).

    Journal: Oncotarget

    Article Title: Targeting tachykinin receptors in neuroblastoma

    doi: 10.18632/oncotarget.13440

    Figure Lengend Snippet: ( A ) Representative flow cytometry images of IMR5, SK-N-AS and SY5Y cells treated with fosaprepitant or control for 72 h and stained for Annexin V and DAPI. Gates show viable cells (DAPI negative, Annexin V negative), early apoptotic cells (DAPI negative, Annexin V positive) and late apoptotic cells (DAPI positive, Annexin V positive) after treatment with fosaprepitant or control. ( B ) Proliferation of cells monitored in real time using the Xcilligance system after fosaprepitant treatment compared with cells treated with Meglumine control ( n = 3, line represents mean value). ( C ) Fraction of cells in each point of the cell cycle measured after 48 h of treatment with fosaprepitant or meglumine (control). ( D ) Bar graph showing cell viability in MTT assays of IMR5 cells treated with 5 μM fosaprepitant or control for 72 h as well as combined fosaprepitant and substance P treatment for 72 h (+ = 100 nM Substance P, ++ = 500 nM Substance P, n = 3, error bars represent the standard deviation)(100nM vs. no substance P, p = 0.0013; 500 nM vs. no substance P, p = 0.0006).

    Article Snippet: The identity of the human neuroblastoma cell lines, IMR5, SK-N-BE, SK-N-AS, SY5Y and Kelly, and foreskin fibroblasts were verified by STR genotyping performed by the German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig, Germany).

    Techniques: Flow Cytometry, Control, Staining, Standard Deviation

    ( A ) Heatmap representation of top 50 dose-sensitive up- (red) and downregulated (blue) genes upon treatment of IMR-5 with fosaprepitant or control (heatmap representation generated by HeatmapViewer of GenePattern servers). ( B ) Dose-dependent mRNA expression changes of E2F2 and TP53 after treatment of IMR5 cells with fosaprepitant or control as measured using gene-expression arrays. ( C ) Western blot of published downstream effectors of TACR1 signaling, SRC and p-SRC, as well as the newly discovered potential downstream target AURB after treatment of IMR5, SY5Y and SK-N-AS with fosaprepitant or control. ( D – F ) Quantification of SRC (D), p-SRC (E) and TACR1 (F) protein expression using densitometry analysis of western immunoblots ( n = 3, error bars indicate standard deviation, * indicates p < 0.05 and ** indicates p < 0.01 as calculated by student's t -test).

    Journal: Oncotarget

    Article Title: Targeting tachykinin receptors in neuroblastoma

    doi: 10.18632/oncotarget.13440

    Figure Lengend Snippet: ( A ) Heatmap representation of top 50 dose-sensitive up- (red) and downregulated (blue) genes upon treatment of IMR-5 with fosaprepitant or control (heatmap representation generated by HeatmapViewer of GenePattern servers). ( B ) Dose-dependent mRNA expression changes of E2F2 and TP53 after treatment of IMR5 cells with fosaprepitant or control as measured using gene-expression arrays. ( C ) Western blot of published downstream effectors of TACR1 signaling, SRC and p-SRC, as well as the newly discovered potential downstream target AURB after treatment of IMR5, SY5Y and SK-N-AS with fosaprepitant or control. ( D – F ) Quantification of SRC (D), p-SRC (E) and TACR1 (F) protein expression using densitometry analysis of western immunoblots ( n = 3, error bars indicate standard deviation, * indicates p < 0.05 and ** indicates p < 0.01 as calculated by student's t -test).

    Article Snippet: The identity of the human neuroblastoma cell lines, IMR5, SK-N-BE, SK-N-AS, SY5Y and Kelly, and foreskin fibroblasts were verified by STR genotyping performed by the German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig, Germany).

    Techniques: Control, Generated, Expressing, Gene Expression, Western Blot, Standard Deviation